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This is because there is always one molecular orbital where all the p orbitals combine in-phase · If there are an even number of atoms, there is also a single molecular orbital highest in energy; otherwise there will be a pair of degenerate molecular orbitals highest in energy · All the molecular orbitals come in degenerate pairs except the one lowest in energy and, for evennumbered systems, the one highest in energy Now we can begin to put all the pieces together and make sense of what we know so far. Let us compare the energy level diagrams for benzene and planar cyclooctatetraene. We are not concerned with the actual shapes of the molecular orbitals involved, just the energies of them. Benzene has six electrons, which means that all its bonding molecular orbitals are fully occupied giving a closed shell structure. Six of these fill up the bonding molecular orbitals but there are two electrons left. The protons attached to an aromatic ring are further downfield than would otherwise be expected (Chapter 11). Using this simple method to work out the energy level diagrams for other rings, we find that there is always a single low-energy bonding orbital (composed of all p orbitals combining in-phase) and then pairs of degenerate orbitals. Since the single orbital will hold two electrons when full and the degenerate pairs four, we shall have a closed shell of electrons in these orbitals only when they contain 2 + 4n electrons (n is an integer 0, 1, 2, etc. Analogous systems with 4n electrons are described as anti-aromatic That the system is fully conjugated and planar are important conditions for aromaticity. The next (4n + 2) number after six is ten so we might expect this cyclic alkene to be aromatic. If this annulene with five cis double bonds were planar, each internal angle would be 144°. Since a normal all-cis-[10]annulene double bond has bond angles of 120°, this would be far from ideal. This compound can be made but it does not adopt a planar conformation and therefore is not aromatic even though it has ten electrons. By contrast, [18]annulene, which is also a (4n + 2) electron system (n = 4), [18]-annulene does adopt a planar conformation and is aromatic (as shown by proton Annulenes (meaning ring alkenes) are compounds with alternating double and single bonds. Taking a simple example, should we consider naphthalene as two benzene rings joined together or as a ten electron system? From its chemistry, it is very clear that naphthalene is aromatic but perhaps a little less so than benzene itself. For example, naphthalene can easily be reduced to tetralin (1,2,3,4-tetrahydronaphthalene) which still contains a benzene ring. Also, in contrast to benzene, all the bond lengths in naphthalene are not the same. Cyclopentadiene, for example, has two double bonds that are conjugated but the whole ring is not conjugated since there is a methylene group in the ring. The energy level the stable cyclopentadienyl anion diagram shows us that six electrons completely fill the bonding molecular orbitals thereby giving a stable structure. However, most aromatic systems are heterocyclic-that is, involving atoms other than carbon and hydrogen. In the cyclopentadiene ring above, there were also two double bonds and on deprotonation one carbon could formally contribute the other two electrons needed for aromaticity. You will meet many aromatic compounds in this book: in Chapter 22 we shall look at the chemistry of benzene and in Chapters 43 and 44 we shall discuss heterocyclic aromatic compounds. We shall finish off this chapter with a few more examples of some common aromatic compounds. In each case the aromatic part of the molecule-which may be one ring or several rings-is outlined in black. When people walk off a building claiming that they can fly, they are probably on acid. It contains an indole ring made up of a benzene ring and a pyrrole ring fused together. It contains a simple benzene ring and a more complex heterocyclic system, which can be divided into two aromatic heterocyclic rings. It contains the aromatic porphyrin ring system with its eighteen electrons arranged in annulene style.

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Theyre also packed with vitamins and minerals, and some of them you cant get as easily by eating the uncooked versions. Thats why it is important you eat lots of fruits and vegetables to have a healthy balance. So if you dont like to eat certain vegetables raw, cook them ­ it is better you eat them cooked than not eat them at all, no matter how many of the nutrients cooking might destroy. And it doesnt really matter whether you cook them or not, as long as youre eating your full servings of greens, reds, and yellows every day. Articles: Finding the Best Way to Cook All Those Vegetables, Tara Parker-Pope, May 20, 2008. How to Cook Vegetables without Losing Their Vitamins and Nutrients, Kristie Leong, M. A proper diet can boost the immune system and help a person stay healthy and disease free even during the dreaded flu season. There are several different vitamins, minerals and food groups that fall in the immune booster category. These booster foods can increase the number of white blood cells and enhance their function while helping to flush non-functioning cells from the body. It increases infection fighting white blood cells and antibodies as well as interferon, which is the antibody that coats cell surfaces and prevents the entry of viruses. Vitamin E It stimulates natural killer cells that seek out and destroy germs, bacteria and even cancer cells. Vitamin E also increases the production of B-cells which produce antibodies and destroy bacteria. Beta-Carotene Beta-carotene increases infection fighting cells, natural killer cells and helper T-cells while decreasing the number of free radicals in the body. Beta-carotene is a powerful antioxidant and helps fight cardiovascular disease by interfering with the way fats oxidize in the blood stream to form plaque. Omega-3 fatty acids and vitamin E complement each other, working together to give a major boost to the immune system. Common foods containing vitamin C include: bell peppers, citrus fruits (oranges, limes, lemons), dark green leafy vegetables (spinach, broccoli, sprouts) and herbs (parsley, thyme). Common foods containing vitamin E include: nuts and seeds (almonds, peanuts, walnuts, sunflower seeds), apples with skin, sweet potatoes and raw spinach. Common foods containing beta-carotene include: naturally orange foods (carrots, pumpkins, sweet potatoes, squash), and leafy greens (spinach, kale, red leaf lettuce, turnip greens). Sweet Autumn Chicken -4 cups chopped butternut squash -4 chopped apples -4 frozen chicken tenders -1 cup apple cider -2 tablespoons butter -Salt and pepper Common foods containing omega-3 fatty acids include: fish/fish oil, flax seed/flax seed oil, walnuts and canola oil. Through a healthy diet consisting of fruits and vegetables we can consume all of the necessary vitamins and minerals. Qian traveled half way around the world to become a Baylor Bear and instantly brought a different dynamic to the volleyball squad. The first time I went to church over here a bunch of people I never met before came up to me and started talking to me. The rules are starting to now change, and I think more families are allowed to have two kids. Also, I think families that live in the country (farmers) are allowed to have more than one child. In the city, you get used to ignoring the sky, you never really see the stars because of all the lights and pollution. My dad played basketball, but he said I was too short for that, so he put me in volleyball. I already lived away from home in middle school and high school, so I was used to that aspect of it. This is even more so now, the only time I get to go home and see my family is at Christmas. Lang Ping is one of the great volleyball players in China, and she was a championship coach for the U. Her first two years at Baylor University she kept to herself, but now she has opened up and shown me her bubbly personality. She has grown in her faith and I can see a new light of happiness shining through her. Ultimately, I would like to get into the field of sports management and maybe coach volleyball.


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To reduce the possibility of costly blank pages, avoid use of new odd pages and halftitles whenever possible. They should be plainly marked showing the desired type, size of type page, illustrations if any, paper, trim, lettering, and binding. In looseleaf or perforated-on-fold work, indicate folio sequence, including blank pages, by circling in blue. This can be done by splitting a would-be fold-in and arranging the material to appear as facing pages in the text. Where fold-ins are numerous and cannot be split, consider folding and inserting these into an envelope pasted to the inside back cover. Every effort should be made to keep complete jobs of over 4 pages to signatures (folded units) of 8, 12, 16, 24, or 32 pages. If nonstandard trim sizes and/or type areas are used, indicate head and back margins. Customers should submit copy for running heads and indicate the numbering sequence for folios, including the preliminary pages. Corrections should be made on first proofs returned, as later proofs are intended for verification only. Corrections should be marked in the margins of a proof opposite the indicated errors, not by writing over the print or between the lines. Used as a planning aid and guide in selecting an adequate grade, weight, and color of paper for a job of printing. Corrections made to proofs should be indicated as follows: 1 In lieu of the traditional mark "tr" used to indicate letter or number transpositions, the striking out of the incorrect letters or numbers and the placement of the correct matter in the margin of the proof is the preferred method of indicating transposition corrections. The placement of corrections in the left-hand margin for those errors found in the left-hand portion of the proof and in the right-hand margin for right-side errors prevents overcrowding of marks and facilitates corrections. New publications are evaluated by application specialists who review their requirements and design the necessary formats. At this time, customer agencies are requested to indicate precise details of any style changes because this set of pages serves as a guide for the copy preparer, the beginning of actual production. Changes in the needs of the library community have led to a move toward uniform treatment of the component parts of publications. In developing standards to guide publishers of Government documents, consideration has been given to the changing needs of those who seek to produce, reference, index, abstract, store, search, and retrieve data. However, when the following elements occur in Government publications, they generally appear in the sequence listed below. The designation "new odd page" generally refers to bookwork and is not required in most pamphlet- and magazinetype publications. An introduction differs from a foreword or a preface in that it is the initial part of the text; if the book is divided into chapters, it should be the first chapter. If some of this preliminary matter is necessary, it is more practical to combine them. Widow lines (lines less than full width of measure) at top of pages are to be avoided, if possible, but are permitted if absolutely necessary to maintain uniform makeup and page depth. If it is found necessary to make a short page, the facing page should be of approximate equal depth. A blank space or sink of 6 picas should be placed at the head of each new odd or even page of 46-pica or greater depth; pages with a depth of from 36 to 45 picas, inclusive, will carry a 5-pica sink; pages less than 36 picas, 4 picas. When centered top folios are used, the folio on a new page is set 2 points smaller than the top folios, centered at the bottom, and enclosed in parentheses. When running heads with top folios are used, running heads are included in overall page depth. However, first pages of chapters and other pages with bottom folios do not include the folios as part of the overall page depth. Jobs that have bottom folios will align them in the margin, including those on preliminary pages. Contents, list of illustrations, preface, or any other matter that makes a page in itself will retain normal 6-pica sink. Footnote references are repeated in boxheads or in continued lines over tables, unless special orders are given not to do so. A landscape or broadside table that continues from an even to an odd page must be positioned to read through the center (gutter) of the publication when its size is not sufficient to fill both pages.

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Two hours later she still complained of nausea, weakness and fatigue, but her vital signs and mental status were normal. The symptoms included dizziness, nausea, vomiting, headache, anxiety, confusion, restlessness and irritability. Two of them were treated with oral cyproheptadine 4 mg either two or three times daily, and the symptoms of all of them resolved within a week. On day 14 simvastatin 10 mg was given to 8 subjects and pravastatin 20 mg was given to the other 8 subjects. Sugimoto K, Ohmori M, Tsuruoka S, Nishiki K, Kawaguchi A, Harada K, Arakawa M, Sakomoto K, Masada M, Miyamori I, Fujimura A. The non-renal clearance of a single dose of talinolol 30 mg given as a 30-minute infusion was increased by about 26%. Other pharmacokinetic parameters of both oral and intravenous talinolol were not significantly affected. The modest decrease in talinolol levels suggests that, in most patients, this interaction is unlikely to be clinically significant. Nevertheless, consider this interaction if blood pressure is difficult to control. In order to achieve target levels, the tacrolimus dose was increased in all patients, from a median of 4. In contrast, no pharmacokinetic interaction was found in a 2-week study in healthy subjects. Importance and management the general clinical importance of this isolated report is uncertain. Both tibolone and hydroxychloroquine sulfate have been associated with liver toxicity alone but cases with hydroxychloroquine sulfate are quite rare. Nevertheless, it may be prudent to be aware of a possible interaction if symptoms of liver toxicity (fatigue, reduced appetite, dark urine) become apparent. Acute hepatitis with prolonged cholestasis and disappearance of interlobular bile ducts following tibolone and Hypericum perforatum (St. No changes in the use of these drugs or altered compliance were identified that might have offered an alternative explanation for the changed theophylline requirements. Despite the isolated case report of a marked decrease in theophylline levels, no significant pharmacokinetic interaction was noted in healthy subjects, and any pharmacokinetic interaction appears likely to be minor. However, until further evidence is available, it would be prudent to be aware of the possibility of an interaction. Importance and management the evidence for an interaction is limited to this study, and based on the minor reduction in amitriptyline levels seen, it seems unlikely that a clinically significant reduction in efficacy would occur. Decreased plasma levels of amitriptyline and its metabolites on comedication with an extract from St. Her liver function normalised after about one year of taking ursodesoxycholic acid 250 mg twice daily. Previous use of eletriptan and fluoxetine had not resulted in any reported adverse effects. After admission to hospital, the patient developed acute rhabdomyolysis and transient mild acute renal failure. Serotonin syndrome was diagnosed, all medications were stopped and the symptoms gradually resolved over 10 days. The possible concern is that concurrent use may result in the development of serotonin syndrome. Serotonin syndrome and rhabdomyolysis induced by concomitant use of triptans, fluoxetine and hypericum. Maurer A, Johne A, Bauer S, Brockmцller J, Donath F, Roots I, Langheinrich M, Hьbner W-D. Constituents the oil from starflower seeds contains the essential fatty acids of the omega-6 series, linoleic acid (about 30 to 41%) and gamolenic acid (gamma-linolenic acid, about 17 to 27%). Other fatty acids include oleic acid, alpha-linolenic acid, palmitic acid and stearic acid. Starflower leaves contain potentially hepatotoxic pyrrolizidine alkaloids including lycopsamine, intermedine and their derivatives.

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For information on the interactions of individual flavonoids present in rooibos, see under flavonoids, page 186. R Use and indications Rooibos teas have been traditionally used in South Africa for a wide range of aliments including asthma, colic, headache, nausea, depression, diabetes and hypertension. Rooibos + Midazolam the interaction between rooibos tea and midazolam is based on experimental evidence only. Rooibos + Iron compounds Rooibos tea does not appear to significantly reduce the absorption of iron. Clinical evidence In a parallel group study in healthy subjects, mean iron absorption after ingestion of radiolabelled iron 16 mg with a beverage was 7. It contains some polyphenolic flavonoids which might bind iron in the gut; however, these differ from the polyphenols found in tea, such as the catechins, which have reported to affect iron absorption. Tannins found in tea are also thought to reduce iron absorption, but rooibos tea has less than 5% tannins. Importance and management the evidence suggests that rooibos does not reduce the absorption of iron. Experimental evidence An in vitro study investigating the effects of rooibos tea on midazolam pharmacokinetics found that a 10% solution of rooibos tea 4 g/L brewed for 5 minutes reduced the levels of the 4-hydroxy metabolite of midazolam to undetectable levels. Importance and management Although the data are limited and there appear to be no clinical studies, it would seem that rooibos tea may have the potential to significantly reduce the levels of midazolam, and therefore reduce its efficacy. Nevertheless, until more is known, it would seem prudent to monitor the outcome of concurrent use, being alert for a decrease in the efficacy of midazolam. For information on the pharmacokinetics of individual flavonoids present in sage, see under flavonoids, page 186. Constituents the major constituents of sage are flavonoids including luteolin and derivatives, caffeic acid derivatives, diterpenes and triterpenes. Salvia officinalis contains the monoterpene hydrocarbons - and -thujones as the major components, together with 1,8-cineole, camphor and borneol, and others. Salvia lavandulifolia does not contain thujones, and Salvia triloba only small amounts, making these oils less toxic. For information on the interactions of individual flavonoids present in sage, see under flavonoids, page 186. It has antiseptic and spasmolytic properties, and a tea infusion is used as a gargle for sore throats. Sage (Salvia lavandulifolia in particular because of the absence of thujones) has recently generated interest as a cognition enhancer due to its anticholinesterase properties. The oil may be applied topically as an antiseptic and rubefacient but it should not be taken internally, applied externally in large amounts or used by pregnant women. Small (Arecaceae) Synonym(s) and related species American dwarf palm, Sabal, Serenoa. Constituents S the fruit of saw palmetto contains about 25% fatty acids (extracts are often standardised to a minimum of 11% total fatty acids) consisting of capric, caprylic, lauric, palmitic, oleic, linoleic and linolenic acids in the form of fixed oils. Sterols including campesterol, stig masterol and -sitosterol are also present, as are long-chain alcohols, carotenoids, various polysaccharides and some flavonoids, including rutin, isoquercetin and kaempferol. For information on the pharmacokinetics of individual flavonoids present in saw palmetto, see under flavonoids, page 186. Interactions overview There may be an increased response to anticoagulant treatment in patients who also take saw palmetto. Saw palmetto does not appear to have a clinically relevant effect on the majority of cytochrome P450 isoenzymes and no other interactions with saw palmetto have been found. For information on the interactions of individual flavonoids present in saw palmetto, see under flavonoids, page 186. Analysis of the inhibitory potential of Ginkgo biloba, Echinacea purpurea, and Serenoa repens on the metabolic activity of cytochrome P450 3A4, 2D6, and 2C9. Use and indications the main contemporary use of saw palmetto fruit is to treat the urological symptoms of benign prostatic hyperplasia. It has also been used as a diuretic, a sedative, an endocrine agent, an antiseptic and for treating disorders involving the sex hormones. Excessive bleeding during surgery has been reported in another patient who had been taking saw palmetto. Curbicin is a herbal remedy used for micturition problems, and contains extracts from the fruit of saw palmetto and the seed of Cucurbita pepo.

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The content of these diets varied substantially, though they tended to emphasize plant based foods, especially fruits and vegetables, legumes, nuts, and whole grains. Fat intake was relatively low at 26 percent of energy (7 percent each monounsaturated and saturated, 10 percent polyunsaturated), compared to 36 percent in the control group. The studies were predominantly observational, but included some trial evidence, and they typically 190 2015 Dietary Guidelines Advisory Committee Report assessed dietary intakes through self-report. Similarly, the majority of studies assessing stroke incidence or mortality reported favorable associations, with the lower stroke risk ranging from 13 to 53 percent for greater adherence to a Mediterranean-style dietary pattern and from 14 to 60 percent for greater adherence to a U. For additional details on this body of evidence, visit: References 2, 10, 11, 14-19 and Appendix E-2. Clinically meaningful weight losses that were achieved ranged from 4 to 12 kilogram at 6-month follow-up. Thereafter, slow weight regain is observed, with total weight loss at 1 year of 4 to 10 kilograms and at 2 years of 3 to 4 kilograms. However, some dietary patterns may be more beneficial in the long-term for cardiometabolic health. Components of the dietary patterns associated with these favorable outcomes include higher intakes of unsaturated fats and lower intakes of saturated fats, cholesterol, and sodium. During childhood and adolescence, a time period critical for the prevention of obesity later in life, a dietary pattern similar to that associated with a healthy weight in adults should be encouraged. Among overweight and obese individuals, an energy deficit is necessary to achieve weight loss. This can be achieved through a variety of evidence-based dietary patterns and should be approached with comprehensive lifestyle interventions. These approaches are best complemented with population-based approaches, as mentioned in Part D. Chapter 4: Food Environment and Settings, which will allow all factors influencing lifestyle behaviors to be addressed as defined in the socio-ecological model. The energy balance equation requires that for weight loss, one must consume less energy than one expends or expend more energy than one consumes. For the different dietary approaches (provided either as part of a comprehensive lifestyle change intervention carried out by a multi-disciplinary team of trained professionals or within nutrition interventions conducted by nutrition professionals) that the authors of the report evaluated, it is evident that all prescribed diets that achieved an energy deficit were associated with weight loss. There was no apparent superiority of one approach when behavioral components were balanced in the treatment arms. Results indicated that average weight loss is maximal at 6 months with smaller losses maintained for up to 2 years, while treatment and follow-up taper. Weight loss achieved by dietary techniques aimed at reducing daily energy intake ranges from 4 to 12 kilograms at 6-month follow-up. The following dietary approaches are associated with weight loss if reduction in dietary energy intake is achieved: x A diet from the European Association for the Study of Diabetes Guidelines, which focuses on targeting food groups, rather than formal prescribed energy restriction while still achieving an energy deficit. Higher protein (25 percent of total calories from protein, 30 percent of total calories from fat, 45 percent of total calories from x x x x x x x x x x x x x carbohydrate) with provision of foods that realized energy deficit. Low-carbohydrate (initially less than 20 g/day carbohydrate) diet without formal prescribed energy restriction but realized energy deficit. Low-fat (10 percent to 25 percent of total calories from fat) vegan-style diet without formal prescribed energy restriction but realized energy deficit. Low-fat (20 percent of total calories from fat) diet without formal prescribed energy restriction but realized energy deficit. Low-glycemic load diet, either with formal prescribed energy restriction or without formal prescribed energy restriction but with realized energy deficit. Macronutrient-targeted diets (15 percent or 25 percent of total calories from protein; 20 percent or 40 percent of total calories from fat; 35 percent, 45 percent, 55 percent, or 65 percent of total calories from carbohydrate) with prescribed energy restriction. Moderate protein (12 percent of total calories from protein, 58 percent of total calories from carbohydrate, 30 percent of total calories from fat) with provision of foods that realized energy deficit. Provision of high-glycemic load or low glycemic load meals with prescribed energy restriction.

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Puritan; puritanical Pyrrhic victory Q Quad Cities (Davenport, Rock Island, Moline, East Moline, and Bettendorf) query queue R Radio Free Europe/Radio Liberty Railroad, Alaska; the railroad Ranch, King, etc. Congress); but lowercased if referring to a State senator, unless preceding a name senatorial Sergeant at Arms (U. Senate or House) Sermon on the Mount server Service, if referring to Federal unit; the Service: Extension Federal Mediation and Conciliation Fish and Wildlife Foreign (see Foreign Service) Forest Internal Revenue Marshals National Park Natural Resources Conservation Postal Secret (Homeland Security) Selective (see also System); but selective service, in general sense; selective service classification 1-A, 4-F, etc. Senior Executive service: airmail Army city delivery consular customs diplomatic employment (State) extension (State) general delivery naval Navy parcel post postal field rural free delivery; rural delivery; free delivery special delivery star route Shelf, Continental (see Continental) ship of state (unless personified) Sister(s) (adherent of religious order) Six Nations (see Indians) Smithsonian Institution (see Institution) Capitalization Examples 75 Social Security Administration (U. Socialist Party; a Socialist Society, if part of name; the society: American Cancer Society, Inc. Southern States Southern United States southerner Southwest, the (section of United States) space shuttle; the shuttle space station spam (email) Spanish-American War (see War) Speaker of the House of Representatives; the Speaker special agent specialist Special Order No. Far Western Gulf; Gulf Coast Lake Latin American lower 48 Middle Middle Atlantic Middle Western Midwestern Mountain New England North Atlantic Northwestern, etc. Treasurer of the United States; the Treasurer Treasury notes; Treasurys Treasury, of the United States; General; National; Public Treaty, if part of name; the treaty: Jay North Atlantic; North Atlantic Defense 78 Chapter 4 of Versailles but treaty of 1919 triad Tribe; Tribal (federally recognized) (see Indians) Tribunal, standing alone capitalized only in minutes and official reports of a specific arbitration; also High Tribunal; the Tribunal (Supreme Court) Tropic of Cancer, of Capricorn; the Tropics tropical; neotropic, neotropical, subtropic(s), subtropical Trust, Power, etc. Paul) U U-boat Under Secretary, if referring to officer of Federal Government; the Under Secretary: of Agriculture of State of the Treasury Uniform Code of Military Justice (see Code) Union (if part of proper name; capitalized standing alone if synonym for United States or if referring to international unit): Columbia Typographical European Pan American (former name; see Organization of American States) Station; but union passenger station; union freight station Teamsters; the Teamsters; the union; also the Auto Workers, etc. Weirs, The; but the Weirs streets welfare state West: Bank (Jordan) Coast (Africa); but west coast (U. Foreign Trade; Foreign Trade Zone; but the foreign trade zone, free trade zone zone: Arctic eastern standard time no-fly polar tropical Zoological Park (National); the zoo; the park 5. Spelling (See also Chapter 7 "Compounding Examples" and Chapter 9 "Abbreviations and Letter Symbols") 5. Colloquial and dialect spellings are not used unless required by the subject matter or specially requested. The tendency of some producers of computer-assisted publications to rely on the limited capability of some spell-checking programs adds importance to this list. Preferred and difficult spellings In addition to indicating the preferred forms of words with variant spellings, the list also contains other words frequently misspelled or causing uncertainty. N naive naivete nee O opera bouffe opera comique P papier mache piece de resistance pleiade porte cochere porte lumiere portiere pousse cafe premiere protege (masc. Plural forms Nouns ending in o immediately preceded by a vowel add s to form the plural; nouns ending in o preceded by a consonant add es to form the plural, except as indicated in the following list. When a noun is hyphenated with an adverb or preposition, the plural is formed on the noun. In forming the plurals of compound terms, the significant word takes the plural form. The following list comprises other words the plurals of which may cause difficulty. The letter l is followed by yze if the word expresses an idea of loosening or separating, as analyze; all other words of this class, except those ending with the suffix wise and those in the following list, end in ize. Only one word ends in sede (supersede); only three end in ceed (exceed, proceed, succeed); all other words of this class end in cede (precede, secede, etc. A single consonant following a single vowel and ending in a monosyllable or a final accented syllable is doubled before a suffix beginning with a vowel. The indefinite article a is used before a consonant and an aspirated h; an is used before a silent h and all vowels except u pronounced as in visual and o pronounced as in one. When a group of initials begins with a, e, f, h, i, l, m, n, o, r, s, or x, each having a vowel sound, the indefinite article an is used. Use of the indefinite article a or an before a numerical expression is determined by the consonant or vowel sound of the beginning syllable. Copy will be followed as to accents, but these should be consistent throughout the entire job. The table on Demonyms in Chapter 17 "Useful Tables" shows forms to be used for nouns and adjectives denoting nationality. Alabamian Alaskan Arizonan Arkansan Californian Coloradan Connecticuter Delawarean Floridian Georgian Hawaii resident Hoosier (Indiana) Idahoan Illinoisan Iowan Kansan Kentuckian Louisianian Mainer Marylander Massachusettsan Michiganian Minnesotan Mississippian Missourian Montanan Nebraskan Nevadan New Hampshirite New Jerseyan New Mexican New Yorker North Carolinian North Dakotan Ohioan Oklahoman Oregonian Pennsylvanian Rhode Islander South Carolinian South Dakotan Tennessean Texan Utahn Vermonter Virginian Washingtonian West Virginian Wisconsinite Wyomingite 96 Chapter 5 5. Observe the following forms: Alaska Native Asian American Black or African American Hispanic or Latino Native American or American Indian Native Hawaiian Pacific Islander Puerto Rican White Native American words 5. Words, including Tribal and other proper names of Indian, Alaska Native, Hawaiian, and other groups, are to be followed literally as to spelling and the use of spaces, diacriticals, hyphens, etc. In the spelling of nongeographic words transliterated from Chinese, Japanese, or any other language that does not have a Latin alphabet, copy is to be followed literally.

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Handbags, with or without shoulder strap or without handle, with outer surface of leather, composition or patent leather, nesoi, over $20 ea. Handbags, with or without shoulder straps or without handle, with outer surface of sheeting of plastics Handbags with or without shoulder strap or without handle, with outer surface of textile materials, wholly or in part of braid, of abaca Handbags with or without shoulder strap or without handle, with outer surface of textile materials, wholly or in part of braid, nesoi Handbags with or without shoulder strap or without handle, with outer surface of cotton, not of pile or tufted construction or braid Handbags with or w/o shoulder strap or w/o handle, outer surface of veg. Laminated wood nesoi, at least 1 nonconiferous outer ply,at least 1 layer of particle board Not blockboard:plywood nesoi,at least 1 nonconiferous outer ply, no particle board,not surf. Corks and stoppers of natural cork, tapered & of a thickness (or length) greater than the maximum diam. Rattan webbing for mats, matting and screens Plaits of rattan and similar products of such plaiting materials, whether or not assembled into strips Products of rattan other than plaits and similar products such as plaiting materials. Natural or artificial abrasive powder or grain on a base of materials nesoi, in forms nesoi Slag wool, rock wool and similar mineral wools, in bulk, sheets or rolls Exfoliated vermiculite, expanded clays, foamed slag and similar expanded mineral materials Mixtures and articles of heat-insulating, sound-insulating or sound-absorbing mineral materials, nesoi Articles of asphalt or of similar material, in rolls Articles of asphalt or of similar material, not in rolls Panels, boards, tiles and similar articles of vegetable fiber, straw or wood wastes, agglomerated with cement, plaster or o/mineral binders Panels, boards, sheets, tiles and similar articles of plaster or comp. Cast or rolled glass, in nonwired sheets, n/colored thru the mass, opacified, flashed, etc. Drawn or blown glass, nesoi, in sheets (other than rectangular), nesoi Surface ground or polished glass, w/absorb. Glass fiber yarns, colored, other than fiberglass rubber reinforcing yarn Glass fiber chopped strands of a length more than 50 mm Fiberglass rubber reinforce cord,of electrically nonconduct. Glass fiber slivers Nonwoven glass fiber mats Nonwoven glass fiber in thin sheets (voiles) Nonwoven glass wool insulation products Nonwoven glass fiber webs, mattresses, boards and similar articles of nonwoven glass fibers, nesoi Woven fiberglass tire cord fabric of rovings,n/o 30 cm wide,of elect. Iron/steel (o/stainless), ropes, cables & cordage, o/th of brass plate wire (o/than stranded wire), n/elect. Iron/steel (o/stainless), plaited bands, slings and the like, not electrically insulated Iron/steel, barbed wire; iron/steel, twisted hoop or single flat wire and loosely twisted double wire, of a kind used for fencing Stainless steel, woven cloth endless bands for machinery, w/meshes not finer than 12 wires to the lineal cm in warp or filling Stainless steel, woven cloth endless bands for machinery, w/meshes finer than 12 but n/finer than 36 wires to the lineal cm warp or filling Stainless steel, Fourdrinier wires for papermaking machines w/94 or more wires to the lineal cm in warp or filling Stainless steel, Fourdrinier wires for papermaking machines w/36 to 93 wires to the lineal cm in warp or filling Stainless steel, woven cloth endless bands for machinery, nesoi, w/meshes finer than 36 wires to the lineal cm in warp or filling Stainless steel, woven cloth (o/than endless bands for machinery), w/meshes not finer than 12 wires to the lineal cm in warp or filling Stainless steel, woven cloth (o/than endless bands for machinery), w/meshes finer 12 but n/finer 36 wires to the lineal cm warp/filling Stainless steel, Fourdrinier wires (o/than endless bands) for papermaking machines,w/meshes 94 or more wire to lineal cm warp/filling Stainless steel, Fourdrinier wires (o/than endless bands) for papermaking machines, w/meshes 36 to 93 wires to the lineal cm warp/filling Stainless steel woven cloth (other than endless band for machinery), nesoi, w/meshes finer than 36 wires to the lineal cm in warp or filling Iron or steel (o/than stainless), woven cloth Iron/steel, grill, netting & fencing, of wire w/maximum x-sect. Pipe cutters, bolt cutters, perforating punches and similar tools, nesoi, and base metal parts thereof Hand-operated non-adjustable spanners and wrenches, and base metal parts thereof Hand-operated adjustable spanners and wrenches, and base metal parts thereof Socket wrenches, with or without handles, drives and extensions, and base metal parts thereof Drilling, threading or tapping tools, and base metal parts thereof Hammers and sledge hammers, with heads not over 1. Tools for working in the hand, pneumatic, other than rotary type, other than suitable for metal working Parts of tools for working in the hand, hydraulic or with self-contained nonelectric or electric motor, other than chain saws Gas-operated machinery, apparatus and appliances, hand-directed or -controlled, used for soldering, brazing, welding or tempering, nesoi Machinery and apparatus, hand-directed or -controlled, used for soldering, brazing or welding, not gas-operated Parts of hand-directed or -controlled machinery, apparatus and appliances used for soldering, brazing, welding or tempering Parts for machinery, apparatus or appliances, not hand-directed or -controlled, used for soldering, brazing, welding or tempering Electronic calculator operate w/o external electric power & pocket-size data recording/reproducing/displaying machine w/calculating function Electronic calculating machines, incorporating a printing device, nesoi Electronic calculating machines, not incorporating a printing device, nesoi Calculating machines nesoi, other than electronic Postage-franking, ticket-issuing and similar machines nesoi, incorporating a calculating device; accounting machines Processing units other than those of subheading 8471. This analysis, in conjunction with in vivo chlorophyll fluorescence measurement and other plant physiological and toxicological techniques, will be used to assess the impact of contaminants on plants. Chlorophylls are light-harvesting pigments integral to the photosynthetic process. The method will be used during the growing season for field applications, or at anytime during the year in laboratory applications. In all instances, the ultimate procedures employed should be documented and associated with the final report. Photosynthetic tissue of a known (measured) area will be ground in a solution of 1 part 0. The slurry is centrifuged and the supernatant is diluted to a concentration that gives an absorbance reading between 0. The absorbance of each solution is recorded at these wavelengths and chlorophyll a and b concentrations are calculated. The foil-wrapped sample will then be placed in a resealable plastic bag and held in darkness. Dry ice may be used to achieve such low temperatures in storage, especially while out in the field. If dry ice or another mode of freezing the tissue is not available, samples can be held on wet ice (4C) for no longer than three days prior to analysis. Darkness must be maintained during the storage period and analyses must be carried out in subdued light to avoid chlorophyll degradation. Also, to avoid degradation, analytical procedures must be performed with opaque containers or containers covered with aluminum foil when it is possible. If necessary, the undiluted extracts can be held at -10C or less for seven days in total darkness in rubber-stoppered borosilicate glass centrifuge tubes wrapped with parafilm to maintain an airtight seal. Additionally, personnel expected to perform this analysis must have experience in basic laboratory procedures and training in this analytical procedure. Equipment required for the laboratory analysis will include a scale, a small pair of scissors, a tissue homogenizer including at least ten glass homogenization tubes with Teflon pestal with 10 mL capacities, tabletop centrifuge, 12 mL borosilicate glass centrifuge tubes, test tube rack, 5 mL and 10 mL pipettes and bulb, spatulas, 10 mL graduated cylinders (at least 10), a visible light spectrophotometer with an optically matched set of cuvettes (1-cm cell size), pasteur pipettes and bulbs, squeeze bottles with acetone and distilled water for rinsing, a freezer, markers, and a logbook. Mix distilled water and reagent-grade acetone in a ratio of 2:8 (v:v) (distilled water:acetone) Additionally, technical-grade acetone should be available for use in the cleaning of glassware.


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If not kept in check, free radicals lead to cell damage linked to chronic diseases. Some nutrients, like vitamins C and E and the mineral selenium, seem to block free radicals directly. In laboratory studies, many individual minerals, vitamins and phytochemicals demonstrate anti-cancer effects. Yet evidence suggests it is the many compounds working together in our overall diet that gives us the strongest cancer protection. The amount you need to eat depends on your age, gender and level of physical activity. For example, instead of eating only apples and bananas from the fruit group, mix it up by enjoying cantaloupe, kiwi fruit, cherries, berries, citrus, grapes, peaches and more. Extra body fat increases the risk for more than 10 types of cancer and other chronic diseases like diabetes and heart disease. The fiber and water in vegetables, fruits, whole grains and beans can help fill you up with fewer calories so losing weight or maintaining your weight is easier. While research continues, the best bets for achieving the maximum health benefits are to: · Eat a diet high in a variety of vegetables, fruits, whole grains and beans · Favor brightly colored or strongly flavored · Stick to food sources-phytochemicals in To include more colorful plant foods in your meals, try: vegetables and fruits, which are often the best sources of phytochemicals supplements (such as pills and powders) may not be as easily absorbed as those from food. To order our free brochures (up to 3 copies) about diet, physical activity and weight management for lower cancer risk, email info@aicr. The Food and Drug Administration is responsible for taking action against any unsafe dietary supplement product after it reaches the market. Some groups of people may benefit from taking supplements for specific health reasons. For more advice tailored to your specific needs, speak to your healthcare provider. We have contributed over $105 million for innovative research conducted at universities, hospitals and research centers across the country. These often use phytochemicals or extracts from foods, and results could be different than results from consuming whole foods. Screening and behavior counseling interventions in primary care to reduce alcohol misuse: U. Behavioral and pharmacotherapy interventions for tobacco smoking cessation in adults, including pregnant women: U. Screening for hepatitis B virus infection in nonpregnant adolescents and adults: U. Screening for intimate partner violence and abuse of elderly and vulnerable adults: U. Aspirin use for the primary prevention of cardiovascular disease and colorectal cancer: U. Behavioral counseling interventions to prevent sexually transmitted infections: U. Behavioral counseling to promote a healthful diet and physical activity for cardiovascular disease prevention in adults with cardiovascular risk factors: U. Behavioral counseling to promote a healthful diet and physical activity for cardiovascular disease prevention in adults without cardiovascular risk factors: U. Vitamins, mineral, and multivitamin supplements for the primary prevention of cardiovascular disease and cancer: U. Preventive Services Task Force recommendation statement [published correction appears in Ann Intern Med. Hormone therapy for the primary prevention of chronic conditions in postmenopausal women: U. Vitamin D, calcium, or combined supplementation for the primary prevention of fractures in community-dwelling adults: U. Screening for peripheral artery disease and cardiovascular disease risk assessment with the ankle-brachial index in adults: U. Screening for suicide risk in adolescents, adults, and older adults in primary care: U. The aril was spray dried at the specified inlet/measured outlet temperatures of 120/66°C, 150/74°C and 170/88°C with/without maltodextrin addition as a drying carrier. The inlet spray drying temperature had significant effects on moisture content, colour, aw, lycopene, -carotene and antioxidant activity of Gac fruit aril powder.

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Beginning with biochemical epidemiological studies of plasma carotenoids, Gey et al. A comparison between median plasma -carotene concentrations and ischemic heart disease mortality revealed no association when all 16 study sites were considered (r2 = 0. Men in the Basel Prospective Study, who had low blood concentrations of -carotene and vitamin C initially and who were followed for 12 years, had a significantly higher risk of subsequent ischemic of Sciences. Total serum carotenoids, measured at baseline in the placebo group of the Lipid Research Clinics Coronary Primary Prevention Trial, were inversely related to subsequent coronary heart disease events (Morris et al. However, because smoking may be part of the causal path, adjustment may not be appropriate. Health Professionals Follow-up Study of over 39,000 men reported a relative risk for coronary heart disease of 0. The effect of -carotene varied by smoking status: among current smokers, the relative risk was 0. A case-control study in 10 European countries found that lycopene concentrations, but not other carotenoid concentrations, in adipose tissue were inversely associated with the risk of myocardial infarction (Kohlmeier et al. Cardiovascular epidemiology studies are now pursuing the use of intermediate endpoints, such as intima-media thickness, which can be estimated via ultrasonography as a measure of atherosclerosis. The macula lutea (macula) is a bright yellow spot in the center of the retina and is specialized and functions to maintain acute central vision. Of all the carotenoids circulating in the body, only two polar species, lutein and zeaxanthin, are contained in the macula (Bone et al. Two groups of investigators have suggested pathways by which these two carotenoids are biochemically interchanged in the macula (Bone et al. Among the specific carotenoids, intake of lutein and zeaxanthin (grouped in the carotenoid food composition database) was most strongly associated with decreased risk. Those in the highest quintile of intake had a 60 percent lower risk compared to the lowest quintile of intake. The study reported protective effects of total carotenoids, -carotene, carotene, -cryptoxanthin, and lutein and zeaxanthin, with odds ratios ranging from 0. Hammond and Fuld (1992) developed an optical system that, in situ, measures the intensity of the unique yellow color of the macula and presumably estimates the levels of lutein and zeaxanthin. Because of the unique metabolism of carotenoids in the macula, this technique will be useful in associating dietary intakes of lutein and zeaxanthin with the health of the macula. Cataracts Cataracts are also problematic, with cataract extraction being the most frequently performed surgical procedure in the elderly (Taylor, 1993). Although the etiology of this condition is not known, oxidative processes may play a role. Cataracts are thought to result from photo-oxidation of lens proteins, resulting in protein damage, accumulation, aggregation, and precipitation in the lens (Taylor, 1993). The cornea and lens filter out ultraviolet light, but visible blue light reaches the retina and may contribute to photic damage or other oxidative insults (Seddon et al. Higher dietary intake of carotenoids or higher blood concentrations of carotenoids have been found to be inversely associated with the risk of various forms of cataract in some, but not all, studies. Jacques and Chylack (1991) reported that subjects with low plasma carotenoid concentrations (those with concentrations less than the twentieth percentile: less than 1. In women, however, higher concentrations of some carotenoids (highest quintile median 2. Health Professionals Follow-up Study reported a relative risk for cataract extraction in men of 0. This decreased risk of cataracts (severe enough to require extraction) with higher intakes of lutein and zeaxanthin was not found with higher intakes of other carotenoids (-carotene, -carotene, lycopene, and -cryptoxanthin) in either of these studies. Plasma and Tissue Concentrations As just detailed, plasma and tissue concentrations of carotenoids have been associated with a variety of health outcomes; that is, higher concentrations are associated with a lower risk of cancer, coronary heart disease, and all-cause mortality. This could be used as a possible indicator for establishing requirements for carotenoids. However, the limitation of this approach is that it is not clear whether observed health benefits are due to carotenoids per se or to other substances found in carotenoid-rich foods. Thus, these data are suggestive of prudent intake levels, not required levels of intake. Recommendations have been made by a number of federal agencies and other organizations with regard to fruit and vegetable intake.


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  • https://biomedres.us/pdfs/BJSTR.MS.ID.004194.pdf
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  • https://publications.armywarcollege.edu/pubs/2201.pdf
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